Aseptic Environment


 

Aseptic Isolation systems provide an environment free from biological hazards and are typically positively pressurized in relation to the room they are located within.  We have developed significant experience in the use of Vaporised Hydrogen Peroxide (VHP), for the effective surface decontamination of the isolators.

A range of multi glove and or half suit Isolators are available that are built custom to each application, which can be bio decontaminated using industry standard integral or free standing automated gassing in place (GIP) systems,  providing a validated 6 log sporicidal reduction plus an overkill of the Isolators' internal surfaces

Restricted-access barrier systems (RABS) which are able to provide a level of aseptic quality are becoming recognised as a solution in some applications as an alternative to the more traditional ‘Isolator'.

 

RABS provide protection by delivering an aerodynamic barrier over a critical process zone and bio-decontamination is usually manual. RABS when installed in ISO 7 environments already have a good class of cleanroom air therefore the RABS can provide ISO 5 in the critical zone.

Because RABS are being used more and more in aseptic processing they have developed to an extent where there are various types of RABS including:

  
  

 

  • Passive RABS, Uses the cleanrooms ventilation system as the source of clean air with barrier guards to prevent operator intervention during the process
  • Active RABS, Provides clean air via HEPA filters by forced ventilation from an on board fan with barrier guards to prevent operator intervention during the process
  • Open RABS, Air once it as passed over the protected zone spills into cleanroom with no additional exhaust filtration
  • Closed RABS, Air when it passes over the critical zone it is filtered before it spills into the cleanroom or is recirculated back through the supply filters of the RABS